Study: ivermectin’s mechanism of action against the SARS-CoV-2 spike protein

Author John Leake has strong opinions on the systematic denial by hospitals to give patients ivermectin—despite the pleas of desperate families.

“The sheer brutality of hospital chiefs and their attorneys, who fought tooth and nail against the administration of ivermectin to dying patients, must surely be the most morally repugnant story in modern medical history,” writes Leake in a guest post on Dr. Peter McCullough’s Substack. “Many patients who were fortunate enough to prevail in court and receive ivermectin enjoyed an astonishing improvement of their condition within 24 hours of receiving their first dose—a recovery that struck family members as miraculous.”

Leake said that in listening to their stories, he often asked himself: “How on earth could this substance (macrocyclic lactone)—derived from a bacteria (Streptomyces avermectinius) found in a soil sample on a golf course in Japan—possibly work such miracles?”

Leake says that it has been known from prior studies on ivermectin that the medicine demonstrates potent anti-viral activity. Nevertheless, the precise mechanism of action was unknown. “Now, thanks to a study recently published by a research team at MEPHI, Aix-Marseille Université, we have a highly plausible description of ivermectin’s mechanism of action against the SARS-CoV-2 spike protein,” said Leake.

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